Structure and activity of the only human RNase T2

Mutations in the gene of human RNase T2 are associated with white matter disease of the human brain. Although brain abnormalities (bilateral temporal lobe cysts and multifocal white matter lesions) and clinical symptoms (psychomotor impairments, spasticity and epilepsy) are well characterized, the p...

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Bibliographic Details
Main Authors: Thorn, Andrea, Steinfeld, Robert, Ziegenbein, Marc, Grapp, Marcel, Hsiao, He-Hsuan, Urlaub, Henning, Sheldrick, George M., Gärtner, Jutta, Krätzner, Ralph
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458558/