In vitro antibacterial and antifungal activities of Cassia fistula Linn. fruit pulp extracts

Aim of the study is to assess the antimicrobial activity Cassia fistula fruit pulp extracts on some bacterial and fungal strains. Hydro alcohol and chloroform extracts of Cassia fistula fruit pulp were evaluated for the potential antimicrobial activity. The antimicrobial activity was determined in b...

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Main Authors:	Bhalodia, N. R., Nariya, P. B., Acharya, R. N., Shukla, V. J.
Format:	Online
Language:	English
Published:	Medknow Publications & Media Pvt Ltd 2012
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3456850/

id	pubmed-3456850
recordtype	oai_dc
spelling	pubmed-34568502012-10-05 In vitro antibacterial and antifungal activities of Cassia fistula Linn. fruit pulp extracts Bhalodia, N. R. Nariya, P. B. Acharya, R. N. Shukla, V. J. Pharmacological Research Aim of the study is to assess the antimicrobial activity Cassia fistula fruit pulp extracts on some bacterial and fungal strains. Hydro alcohol and chloroform extracts of Cassia fistula fruit pulp were evaluated for the potential antimicrobial activity. The antimicrobial activity was determined in both the extracts using the agar disc diffusion method. Extracts were effective on tested microorganisms. The antibacterial and antifungal activities of solvent extracts (5, 25, 50, 100, 250 μg/mL) of C. fistula were tested against two gram positive, two gram negative human pathogenic bacteria and three fungi, respectively. Crude extracts of C. fistula exhibited moderate to strong activity against most of the bacteria tested. The tested bacterial strains were Staphylococcus aureus, Streptococcus pyogenes, Escherichia coil, Pseudomonas aeruginosa, and fungal strains were Aspergillus. niger, Aspergillus. clavatus, Candida albicans. The antibacterial potential of the extracts were found to be dose dependent. The antibacterial activities of the C. fistula were due to the presence of various secondary metabolites. Hence, these plants can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals research activities. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3456850/ /pubmed/23049197 http://dx.doi.org/10.4103/0974-8520.100329 Text en Copyright: © AYU (An International Quarterly Journal of Research in Ayurveda) http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Bhalodia, N. R. Nariya, P. B. Acharya, R. N. Shukla, V. J.
spellingShingle	Bhalodia, N. R. Nariya, P. B. Acharya, R. N. Shukla, V. J. In vitro antibacterial and antifungal activities of Cassia fistula Linn. fruit pulp extracts
author_facet	Bhalodia, N. R. Nariya, P. B. Acharya, R. N. Shukla, V. J.
author_sort	Bhalodia, N. R.
title	In vitro antibacterial and antifungal activities of Cassia fistula Linn. fruit pulp extracts
title_short	In vitro antibacterial and antifungal activities of Cassia fistula Linn. fruit pulp extracts
title_full	In vitro antibacterial and antifungal activities of Cassia fistula Linn. fruit pulp extracts
title_fullStr	In vitro antibacterial and antifungal activities of Cassia fistula Linn. fruit pulp extracts
title_full_unstemmed	In vitro antibacterial and antifungal activities of Cassia fistula Linn. fruit pulp extracts
title_sort	in vitro antibacterial and antifungal activities of cassia fistula linn. fruit pulp extracts
description	Aim of the study is to assess the antimicrobial activity Cassia fistula fruit pulp extracts on some bacterial and fungal strains. Hydro alcohol and chloroform extracts of Cassia fistula fruit pulp were evaluated for the potential antimicrobial activity. The antimicrobial activity was determined in both the extracts using the agar disc diffusion method. Extracts were effective on tested microorganisms. The antibacterial and antifungal activities of solvent extracts (5, 25, 50, 100, 250 μg/mL) of C. fistula were tested against two gram positive, two gram negative human pathogenic bacteria and three fungi, respectively. Crude extracts of C. fistula exhibited moderate to strong activity against most of the bacteria tested. The tested bacterial strains were Staphylococcus aureus, Streptococcus pyogenes, Escherichia coil, Pseudomonas aeruginosa, and fungal strains were Aspergillus. niger, Aspergillus. clavatus, Candida albicans. The antibacterial potential of the extracts were found to be dose dependent. The antibacterial activities of the C. fistula were due to the presence of various secondary metabolites. Hence, these plants can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals research activities.
publisher	Medknow Publications & Media Pvt Ltd
publishDate	2012
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3456850/
_version_	1611911539220021248

In vitro antibacterial and antifungal activities of Cassia fistula Linn. fruit pulp extracts

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