Adoptive Immunotherapy with Cl-IB-MECA-Treated CD8+ T Cells Reduces Melanoma Growth in Mice

Adoptive Immunotherapy with Cl-IB-MECA-Treated CD8+ T Cells Reduces Melanoma Growth in Mice

Cl-IB-MECA is a selective A3 adenosine receptor agonist, which plays a crucial role in limiting tumor progression. In mice, Cl-IB-MECA administration enhances the anti-tumor T cell-mediated response. However, little is known about the activity of Cl-IB-MECA on CD8+ T cells. The aim of this study was...

Full description

Bibliographic Details
Main Authors: Montinaro, Antonella, Forte, Giovanni, Sorrentino, Rosalinda, Luciano, Antonio, Palma, Giuseppe, Arra, Claudio, Adcock, Ian M., Pinto, Aldo, Morello, Silvana
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454429/

Similar Items

Similar Items