Interpretation of the Consequences of Mutations in Protein Kinases: Combined Use of Bioinformatics and Text Mining

Protein kinases play a crucial role in a plethora of significant physiological functions and a number of mutations in this superfamily have been reported in the literature to disrupt protein structure and/or function. Computational and experimental research aims to discover the mechanistic connectio...

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Bibliographic Details
Main Authors: Izarzugaza, Jose M. G., Krallinger, Martin, Valencia, Alfonso
Format: Online
Language:English
Published: Frontiers Research Foundation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449330/