MDM2 Expression Is Repressed by The RNA-Binding Protein RNPC1 via mRNA Stability

The RNA-binding protein RNPC1 is a target of the p53 family and forms a feedback regulatory loop with the p53 family proteins. The MDM2 oncogene, a key negative regulator of p53, plays a critical role in a variety of fundamental cellular processes. MDM2 expression is found to be regulated via gene a...

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Bibliographic Details
Main Authors: Xu, Enshun, Zhang, Jin, Chen, Xinbin
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449025/