Castleman disease mimicked pancreatic carcinoma: report of two cases
Castleman disease (CD) is an uncommon benign lymphoproliferative disorder, which usually presents as solitary or multiple masses in the mediastinum. Peripancreatic CD was rarely reported. Herein, we report two cases of unicentric peripancreatic CD from our center. A 43-year-old man and a 58-year-old...
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| Format: | Online |
| Language: | English |
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BioMed Central
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447677/ |
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pubmed-3447677 |
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pubmed-34476772012-09-21 Castleman disease mimicked pancreatic carcinoma: report of two cases Guo, Hua Shen, Yan Wang, Wei-Lin Zhang, Min Li, Hong Wu, Ying-Sheng Yan, Sheng Xu, Xiao Wu, Jian Zheng, Shu-Sen Case Report Castleman disease (CD) is an uncommon benign lymphoproliferative disorder, which usually presents as solitary or multiple masses in the mediastinum. Peripancreatic CD was rarely reported. Herein, we report two cases of unicentric peripancreatic CD from our center. A 43-year-old man and a 58-year-old woman were detected to have a pancreatic mass in the routine medical examinations. Both of them were asymptomatic. The computed tomography and ultrasonographic examination revealed a mild enhancing solitary mass at the pancreatic head/neck. No definite preoperative diagnosis was established and Whipple operations were originally planned. The intraoperative frozen section diagnosis of both patients revealed lymphoproliferation. Then the local excisions of mass were performed. Histological examination revealed features of CD of hyaline-vascular type. No recurrence was found during the follow-up period. CD should be included in the differential diagnosis of pancreatic tumors. Local excision is a suitable surgical choice. BioMed Central 2012-07-23 /pmc/articles/PMC3447677/ /pubmed/22824621 http://dx.doi.org/10.1186/1477-7819-10-154 Text en Copyright ©2012 Guo et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Guo, Hua Shen, Yan Wang, Wei-Lin Zhang, Min Li, Hong Wu, Ying-Sheng Yan, Sheng Xu, Xiao Wu, Jian Zheng, Shu-Sen |
| spellingShingle |
Guo, Hua Shen, Yan Wang, Wei-Lin Zhang, Min Li, Hong Wu, Ying-Sheng Yan, Sheng Xu, Xiao Wu, Jian Zheng, Shu-Sen Castleman disease mimicked pancreatic carcinoma: report of two cases |
| author_facet |
Guo, Hua Shen, Yan Wang, Wei-Lin Zhang, Min Li, Hong Wu, Ying-Sheng Yan, Sheng Xu, Xiao Wu, Jian Zheng, Shu-Sen |
| author_sort |
Guo, Hua |
| title |
Castleman disease mimicked pancreatic carcinoma: report of two cases |
| title_short |
Castleman disease mimicked pancreatic carcinoma: report of two cases |
| title_full |
Castleman disease mimicked pancreatic carcinoma: report of two cases |
| title_fullStr |
Castleman disease mimicked pancreatic carcinoma: report of two cases |
| title_full_unstemmed |
Castleman disease mimicked pancreatic carcinoma: report of two cases |
| title_sort |
castleman disease mimicked pancreatic carcinoma: report of two cases |
| description |
Castleman disease (CD) is an uncommon benign lymphoproliferative disorder, which usually presents as solitary or multiple masses in the mediastinum. Peripancreatic CD was rarely reported. Herein, we report two cases of unicentric peripancreatic CD from our center. A 43-year-old man and a 58-year-old woman were detected to have a pancreatic mass in the routine medical examinations. Both of them were asymptomatic. The computed tomography and ultrasonographic examination revealed a mild enhancing solitary mass at the pancreatic head/neck. No definite preoperative diagnosis was established and Whipple operations were originally planned. The intraoperative frozen section diagnosis of both patients revealed lymphoproliferation. Then the local excisions of mass were performed. Histological examination revealed features of CD of hyaline-vascular type. No recurrence was found during the follow-up period. CD should be included in the differential diagnosis of pancreatic tumors. Local excision is a suitable surgical choice. |
| publisher |
BioMed Central |
| publishDate |
2012 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447677/ |
| _version_ |
1611910577550000128 |