A Complex Interaction between Rickettsia conorii and Dickkopf-1 – Potential Role in Immune Evasion Mechanisms in Endothelial Cells

A Complex Interaction between Rickettsia conorii and Dickkopf-1 – Potential Role in Immune Evasion Mechanisms in Endothelial Cells

The pathophysiological hallmark of spotted fever group rickettsioses comprises vascular inflammation. Based on the emerging importance of the wingless (Wnt) pathways in inflammation and vascular biology, we hypothesized that Dickkopf-1 (DKK-1), as a major modulator of Wnt signaling, could be involve...

Full description

Bibliographic Details
Main Authors: Astrup, Elisabeth, Lekva, Tove, Davì, Giovanni, Otterdal, Kari, Santilli, Francesca, Øie, Erik, Halvorsen, Bente, Damås, Jan Kristian, Raoult, Didier, Vitale, Giustina, Olano, Juan P., Ueland, Thor, Aukrust, Pål
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445570/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445570/

Similar Items