Increased Metallothionein I/II Expression in Patients with Temporal Lobe Epilepsy

In the central nervous system, zinc is released along with glutamate during neurotransmission and, in excess, can promote neuronal death. Experimental studies have shown that metallothioneins I/II (MT-I/II), which chelate free zinc, can affect seizures and reduce neuronal death after status epilepti...

Full description

Bibliographic Details
Main Authors: Peixoto-Santos, José Eduardo, Galvis-Alonso, Orfa Yineth, Velasco, Tonicarlo Rodrigues, Kandratavicius, Ludmyla, Assirati, João Alberto, Carlotti, Carlos Gilberto, Scandiuzzi, Renata Caldo, Serafini, Luciano Neder, Leite, João Pereira
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445538/