Inhibition of Bacterial Virulence: Drug-Like Molecules Targeting the Salmonella enterica PhoP Response Regulator
Two-component signal transduction (TCST) is the predominant signaling scheme used in bacteria to sense and respond to environmental changes in order to survive and thrive. A typical TCST system consists of a sensor histidine kinase to detect external signals and an effector response regulator to res...
Main Authors: | , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Blackwell Publishing Ltd
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445336/ |