Mast Cell Leukaemia: c-KIT Mutations Are Not Always Positive

Mast cell leukemia (MCL) is a rare and aggressive disease with poor prognosis and short survival time. D816V c-KIT mutation is the most frequent molecular abnormality and plays a crucial role in the pathogenesis and development of the disease. Thus, comprehensive diagnostic investigations and molecu...

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Bibliographic Details
Main Authors: Joris, Magalie, Georgin-Lavialle, Sophie, Chandesris, Marie-Olivia, Lhermitte, Ludovic, Claisse, Jean-François, Canioni, Danielle, Hanssens, Katia, Damaj, Gandhi, Hermine, Olivier, Hamidou, Mohammed
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444844/