Intracerebral immune complex formation induces inflammation in the brain that depends on Fc receptor interaction
In this study, we investigate the underlying mechanisms of antibody-mediated inflammation in the brain. We show that immune complexes formed in the brain parenchyma generate a robust and long-lasting inflammatory response, characterized by increased expression of the microglia markers CD11b, CD68 an...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer-Verlag
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444701/ |