Nutraceutical Interventions for Promoting Healthy Aging in Invertebrate Models

Aging is a complex and inevitable biological process that is associated with numerous chronically debilitating health effects. Development of effective interventions for promoting healthy aging is an active but challenging area of research. Mechanistic studies in various model organisms, noticeably...

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Main Authors:	Dong, Yuqing, Guha, Sujay, Sun, Xiaoping, Cao, Min, Wang, Xiaoxia, Zou, Sige
Format:	Online
Language:	English
Published:	Hindawi Publishing Corporation 2012
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444043/

id	pubmed-3444043
recordtype	oai_dc
spelling	pubmed-34440432012-09-18 Nutraceutical Interventions for Promoting Healthy Aging in Invertebrate Models Dong, Yuqing Guha, Sujay Sun, Xiaoping Cao, Min Wang, Xiaoxia Zou, Sige Review Article Aging is a complex and inevitable biological process that is associated with numerous chronically debilitating health effects. Development of effective interventions for promoting healthy aging is an active but challenging area of research. Mechanistic studies in various model organisms, noticeably two invertebrates, Caenorhabditis elegans and Drosophila melanogaster, have identified many genes and pathways as well as dietary interventions that modulate lifespan and healthspan. These studies have shed light on some of the mechanisms involved in aging processes and provide valuable guidance for developing efficacious aging interventions. Nutraceuticals made from various plants contain a significant amount of phytochemicals with diverse biological activities. Phytochemicals can modulate many signaling pathways that exert numerous health benefits, such as reducing cancer incidence and inflammation, and promoting healthy aging. In this paper, we outline the current progress in aging intervention studies using nutraceuticals from an evolutionary perspective in invertebrate models. Hindawi Publishing Corporation 2012 2012-09-06 /pmc/articles/PMC3444043/ /pubmed/22991584 http://dx.doi.org/10.1155/2012/718491 Text en Copyright © 2012 Yuqing Dong et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Dong, Yuqing Guha, Sujay Sun, Xiaoping Cao, Min Wang, Xiaoxia Zou, Sige
spellingShingle	Dong, Yuqing Guha, Sujay Sun, Xiaoping Cao, Min Wang, Xiaoxia Zou, Sige Nutraceutical Interventions for Promoting Healthy Aging in Invertebrate Models
author_facet	Dong, Yuqing Guha, Sujay Sun, Xiaoping Cao, Min Wang, Xiaoxia Zou, Sige
author_sort	Dong, Yuqing
title	Nutraceutical Interventions for Promoting Healthy Aging in Invertebrate Models
title_short	Nutraceutical Interventions for Promoting Healthy Aging in Invertebrate Models
title_full	Nutraceutical Interventions for Promoting Healthy Aging in Invertebrate Models
title_fullStr	Nutraceutical Interventions for Promoting Healthy Aging in Invertebrate Models
title_full_unstemmed	Nutraceutical Interventions for Promoting Healthy Aging in Invertebrate Models
title_sort	nutraceutical interventions for promoting healthy aging in invertebrate models
description	Aging is a complex and inevitable biological process that is associated with numerous chronically debilitating health effects. Development of effective interventions for promoting healthy aging is an active but challenging area of research. Mechanistic studies in various model organisms, noticeably two invertebrates, Caenorhabditis elegans and Drosophila melanogaster, have identified many genes and pathways as well as dietary interventions that modulate lifespan and healthspan. These studies have shed light on some of the mechanisms involved in aging processes and provide valuable guidance for developing efficacious aging interventions. Nutraceuticals made from various plants contain a significant amount of phytochemicals with diverse biological activities. Phytochemicals can modulate many signaling pathways that exert numerous health benefits, such as reducing cancer incidence and inflammation, and promoting healthy aging. In this paper, we outline the current progress in aging intervention studies using nutraceuticals from an evolutionary perspective in invertebrate models.
publisher	Hindawi Publishing Corporation
publishDate	2012
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444043/
_version_	1611909311558057984

Nutraceutical Interventions for Promoting Healthy Aging in Invertebrate Models

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