Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53

Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53

Poly-ADP ribose polymerase (PARP) inhibitors have shown promise in the treatment of human malignancies characterized by deficiencies in the DNA damage repair proteins BRCA1 and BRCA2 and preclinical studies have demonstrated the potential effectiveness of PARP inhibitors in targeting ataxia-telangie...

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Bibliographic Details
Main Authors: Williamson, Chris T, Kubota, Eiji, Hamill, Jeffrey D, Klimowicz, Alexander, Ye, Ruiqiong, Muzik, Huong, Dean, Michelle, Tu, LiRen, Gilley, David, Magliocco, Anthony M, McKay, Bruce C, Bebb, D Gwyn, Lees-Miller, Susan P
Format: Online
Language:English
Published: WILEY-VCH Verlag 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443945/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443945/

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