Mapping of lamin A- and progerin-interacting genome regions

Mutations in the A-type lamins A and C, two major components of the nuclear lamina, cause a large group of phenotypically diverse diseases collectively referred to as laminopathies. These conditions often involve defects in chromatin organization. However, it is unclear whether A-type lamins interac...

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Bibliographic Details
Main Authors: Kubben, Nard, Adriaens, Michiel, Meuleman, Wouter, Voncken, Jan Willem, van Steensel, Bas, Misteli, Tom
Format: Online
Language:English
Published: Springer-Verlag 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443488/