The catalytic and the RNA subunits of human telomerase are required to immortalize equid primary fibroblasts
Many human primary somatic cells can be immortalized by inducing telomerase activity through the exogenous expression of the human telomerase catalytic subunit (hTERT). This approach has been extended to the immortalization of cell lines from several mammals. Here, we show that hTERT expression is n...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer-Verlag
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443485/ |