Association of Lis1 with outer arm dynein is modulated in response to alterations in flagellar motility

The cytoplasmic dynein regulatory factor Lis1, which induces a persistent tight binding to microtubules and allows for transport of cargoes under high-load conditions, is also present in motile cilia/flagella. Lis1 levels in cilia/flagella are dynamically modulated in response to imposed alterations...

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Bibliographic Details
Main Authors: Rompolas, Panteleimon, Patel-King, Ramila S., King, Stephen M.
Format: Online
Language:English
Published: The American Society for Cell Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442404/