Association of Lis1 with outer arm dynein is modulated in response to alterations in flagellar motility
The cytoplasmic dynein regulatory factor Lis1, which induces a persistent tight binding to microtubules and allows for transport of cargoes under high-load conditions, is also present in motile cilia/flagella. Lis1 levels in cilia/flagella are dynamically modulated in response to imposed alterations...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
The American Society for Cell Biology
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442404/ |