Mitochondrial DNA deletions are associated with non-B DNA conformations

Mitochondrial DNA (mtDNA) deletions are a primary cause of mitochondrial disease and are believed to contribute to the aging process and to various neurodegenerative diseases. Despite strong observational and experimental evidence, the molecular basis of the deletion process remains obscure. In this...

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Bibliographic Details
Main Authors: Damas, Joana, Carneiro, João, Gonçalves, Joana, Stewart, James B., Samuels, David C., Amorim, António, Pereira, Filipe
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439893/