Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects

Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects

Temporal lobe epilepsy is a common, chronic neurologic disorder characterized by recurrent spontaneous seizures. MicroRNAs (miRNAs) are small, non-coding RNAs that regulate post-transcriptional expression of protein-coding mRNAs, which may have important roles in the pathogenesis of neurologic disor...

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Bibliographic Details
Main Authors: Jimenez-Mateos, Eva M., Engel, Tobias, Merino-Serrais, Paula, McKiernan, Ross C., Tanaka, Katsuhiro, Mouri, Genshin, Sano, Takanori, O’Tuathaigh, Colm, Waddington, John L., Prenter, Suzanne, Delanty, Norman, Farrell, Michael A., O’Brien, Donncha F., Conroy, Ronán M., Stallings, Raymond L., deFelipe, Javier, Henshall, David C.
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438344/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438344/

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