Doxorubicin and NRG-1/erbB4-Deficiency Affect Gene Expression Profile: Involving Protein Homeostasis in Mouse
The accumulating evidence demonstrates the essential role of neuregulin-1 signaling in the adult heart, and, moreover, indicates that an impaired neuregulin signaling exacerbates the doxorubicin-mediated cardiac toxicity. Despite this strong data, the specific cardiomyocyte targets of the active erb...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
International Scholarly Research Network
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437290/ |