Human neuronal uncoupling proteins 4 and 5 (UCP4 and UCP5): structural properties, regulation, and physiological role in protection against oxidative stress and mitochondrial dysfunction

Human neuronal uncoupling proteins 4 and 5 (UCP4 and UCP5): structural properties, regulation, and physiological role in protection against oxidative stress and mitochondrial dysfunction

Uncoupling proteins (UCPs) belong to a large family of mitochondrial solute carriers 25 (SLC25s) localized at the inner mitochondrial membrane. UCPs transport protons directly from the intermembrane space to the matrix. Of five structural homologues (UCP1 to 5), UCP4 and 5 are principally expressed...

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Bibliographic Details
Main Authors: Ramsden, David B, Ho, Philip W-L, Ho, Jessica W-M, Liu, Hui-Fang, So, Danny H-F, Tse, Ho-Man, Chan, Koon-Ho, Ho, Shu-Leong
Format: Online
Language:English
Published: Blackwell Publishing Inc 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432969/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432969/

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