miR-421 and miR-30c Inhibit SERPINE 1 Gene Expression in Human Endothelial Cells

In this work, we assessed whether SERPINE1 expression could be under the influence of microRNAs (miRNAs) predicted to bind the SERPINE1 3′UTR region. We specifically focused on the 3′UTR region harboring a common polymorphism, rs1050955, that have been found associated to SERPINE1 monocyte expressio...

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Bibliographic Details
Main Authors: Marchand, Alexandre, Proust, Carole, Morange, Pierre-Emmanuel, Lompré, Anne-Marie, Trégouët, David-Alexandre
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432110/