Effective Gene Trapping Mediated by Sleeping Beauty Transposon

Gene trapping is a high-throughput approach to elucidate gene functions by disrupting and recapitulating expression of genes in a target genome. A number of transposon-based gene-trapping systems are developed for mutagenesis in cells and model organisms, but there is still much room for the improve...

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Bibliographic Details
Main Authors: Song, Guili, Li, Qing, Long, Yong, Gu, Qilin, Hackett, Perry B., Cui, Zongbin
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432063/