Dual effect of heat shock on DNA replication and genome integrity
The data presented here suggest that in an asynchronous cell culture, heat shock might affect DNA integrity both directly and via arrest of replication fork progression and that the phosphorylation of histone H2AX has a protective effect on the arrested replication forks in addition to its known DNA...
| Main Authors: | , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2012
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431931/ |