p53 Inactivation Upregulates p73 Expression through E2F-1 Mediated Transcription

p53 Inactivation Upregulates p73 Expression through E2F-1 Mediated Transcription

While p73 overexpression has been associated with increased apoptosis in cancer tissues, p73 overexpressing tumors appear to be of high grade malignancy. Why this putative tumor suppressor is overexpressed in cancer cells and what the function of overexpressed p73 is in breast cancers are critical q...

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Bibliographic Details
Main Authors: Tophkhane, Chaitali, Yang, Shi-He, Jiang, Yunbo, Ma, Zhikun, Subramaniam, Dharmalingam, Anant, Shrikant, Yogosawa, Shingo, Sakai, Toshiyuki, Liu, Wan-Guo, Edgerton, Susan, Thor, Ann, Yang, Xiaohe
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431388/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431388/

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