New Insights on the Sialidase Protein Family Revealed by a Phylogenetic Analysis in Metazoa

Sialidases are glycohydrolytic enzymes present from virus to mammals that remove sialic acid from oligosaccharide chains. Four different sialidase forms are known in vertebrates: the lysosomal NEU1, the cytosolic NEU2 and the membrane-associated NEU3 and NEU4. These enzymes modulate the cell sialic...

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Bibliographic Details
Main Authors: Giacopuzzi, Edoardo, Bresciani, Roberto, Schauer, Roland, Monti, Eugenio, Borsani, Giuseppe
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431349/