Efficient Hepatitis C Virus Particle Formation Requires Diacylglycerol Acyltransferase 1 (DGAT1)
Hepatitis C virus (HCV) infection is closely tied to the lipid metabolism of liver cells. Here, we identify the triglyceride-synthesizing enzyme DGAT1 as an important host factor for HCV infection; DGAT1 interacts with the viral nucleocapsid core and is required for the trafficking of core to lipid...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431199/ |