The Application of a Three-Step Serum Proteome Analysis for the Discovery and Identification of Novel Biomarkers of Hepatocellular Carcinoma

The representative tumor markers for HCC, AFP, and PIVKA-II are not satisfactory in terms of sensitivity and specificity in the early diagnosis of HCC. In search for novel markers for HCC, three-step proteome analyses were carried out in serum samples obtained from 12 patients with HCC and 10 with L...

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Bibliographic Details
Main Authors: Kimura, Asako, Sogawa, Kazuyuki, Satoh, Mamoru, Kodera, Yoshio, Yokosuka, Osamu, Tomonaga, Takeshi, Nomura, Fumio
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431084/