The N-terminus of mature human frataxin is intrinsically unfolded
Frataxin is a highly conserved nuclear-encoded mitochondrial protein whose deficiency is the primary cause of Friedreich’s ataxia, an autosomal recessive neurodegenerative disease. The frataxin structure comprises a well-characterized globular domain that is present in all species and is preceded in...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Blackwell Publishing Ltd
2009
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430858/ |