Endogenous Fluorescence Signatures in Living Pluripotent Stem Cells Change with Loss of Potency

The therapeutic potential of stem cells is limited by the non-uniformity of their phenotypic state. Thus it would be advantageous to noninvasively monitor stem cell status. Driven by this challenge, we employed multidimensional multiphoton microscopy to quantify changes in endogenous fluorescence oc...

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Bibliographic Details
Main Authors: Squirrell, Jayne M., Fong, Jimmy J., Ariza, Carlos A., Mael, Amber, Meyer, Kassondra, Shevde, Nirupama K., Roopra, Avtar, Lyons, Gary E., Kamp, Timothy J., Eliceiri, Kevin W., Ogle, Brenda M.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430704/