Molecular Mechanisms of Ursodeoxycholic Acid Toxicity & Side Effects: Ursodeoxycholic Acid Freezes Regeneration & Induces Hibernation Mode
Ursodeoxycholic acid (UDCA) is a steroid bile acid approved for primary biliary cirrhosis (PBC). UDCA is reported to have “hepato-protective properties”. Yet, UDCA has “unanticipated” toxicity, pronounced by more than double number of deaths, and eligibility for liver transplantation compared to the...
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| Format: | Online |
| Language: | English |
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Molecular Diversity Preservation International (MDPI)
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430272/ |