L-2-Oxothiazolidine-4-Carboxylic Acid or α-Lipoic Acid Attenuates Airway Remodeling: Involvement of Nuclear Factor-κB (NF-κB), Nuclear Factor Erythroid 2p45-Related Factor-2 (Nrf2), and Hypoxia-Inducible Factor (HIF)
Reactive oxygen species (ROS) play a crucial role in the pathogenesis of acute and chronic respiratory diseases. Antioxidants have been found to ameliorate airway inflammation and hyperresponsiveness in animal models employing short-term exposure to allergen. However, little data are available on th...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Molecular Diversity Preservation International (MDPI)
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430212/ |