TLR4 signaling induces the release of microparticles by tumor cells that regulate inflammatory cytokine IL-6 of macrophages via microRNA let-7b
Tumor cells expressing TLRs is generally recognized to mediate tumor inflammation. However, whether and how tumor TLR signaling pathways negatively regulate tumor inflammation remains unclear. In this report, we find that TLR4 signaling of H22 hepatocarcinoma tumor cells is transduced through MyD88...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Landes Bioscience
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429572/ |