Toll-Like Receptor (TLR2 and TLR4) Polymorphisms and Chronic Obstructive Pulmonary Disease

Toll-like receptors (TLRs) participate in the defence against bacterial infections that are common in patients with Chronic Obstructive Pulmonary Disease (COPD). We studied all tagging SNPs in TLR2 and TLR4 and their associations with the level and change over time of both FEV1 and sputum inflammato...

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Bibliographic Details
Main Authors: Budulac, Simona E., Boezen, H. Marike, Hiemstra, Pieter S., Lapperre, Therese S., Vonk, Judith M., Timens, Wim, Postma, Dirkje S.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429472/