Xenogeneic Graft-versus-Host-Disease in NOD-scid IL-2Rγnull Mice Display a T-Effector Memory Phenotype

The occurrence of Graft-versus-Host Disease (GvHD) is a prevalent and potentially lethal complication that develops following hematopoietic stem cell transplantation. Humanized mouse models of xenogeneic-GvHD based upon immunodeficient strains injected with human peripheral blood mononuclear cells (...

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Bibliographic Details
Main Authors: Ali, Niwa, Flutter, Barry, Sanchez Rodriguez, Robert, Sharif-Paghaleh, Ehsan, Barber, Linda D., Lombardi, Giovanna, Nestle, Frank O.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429415/