An extracellular mechanism that can explain the neurotoxic effects of α-synuclein aggregates in the brain

Neurodegenerative diseases, such as Parkinson's disease (PD), Alzheimer's disease (AD), and Dementia with Lewy bodies (DLB), display an accumulation of proteins including α-synuclein aggregates in cortical and subcortical regions of the brain. PD is a complex, progressive disease which inv...

Full description

Bibliographic Details
Main Authors: Pacheco, C., Aguayo, L. G., Opazo, C.
Format: Online
Language:English
Published: Frontiers Media S.A. 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429068/