Understanding complexity in neurodegenerative diseases: in silico reconstruction of emergence

Healthy functioning is an emergent property of the network of interacting biomolecules that comprise an organism. It follows that disease (a network shift that causes malfunction) is also an emergent property, emerging from a perturbation of the network. On the one hand, the biomolecular network of...

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Bibliographic Details
Main Authors: Kolodkin, Alexey, Simeonidis, Evangelos, Balling, Rudi, Westerhoff, Hans V.
Format: Online
Language:English
Published: Frontiers Media S.A. 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429063/