Antibody Constant Region Peptides Can Display Immunomodulatory Activity through Activation of the Dectin-1 Signalling Pathway

Antibody Constant Region Peptides Can Display Immunomodulatory Activity through Activation of the Dectin-1 Signalling Pathway

We previously reported that a synthetic peptide with sequence identical to a CDR of a mouse monoclonal antibody specific for difucosyl human blood group A exerted an immunomodulatory activity on murine macrophages. It was therapeutic against systemic candidiasis without possessing direct candidacida...

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Bibliographic Details
Main Authors: Gabrielli, Elena, Pericolini, Eva, Cenci, Elio, Monari, Claudia, Magliani, Walter, Ciociola, Tecla, Conti, Stefania, Gatti, Rita, Bistoni, Francesco, Polonelli, Luciano, Vecchiarelli, Anna
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428300/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428300/

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