High-fat-diet exposure induces IgG accumulation in hypothalamic microglia

The mediobasal hypothalamic arcuate nucleus (ARC), with its relatively ‘leaky’ blood-brain barrier that allows more circulating molecules to enter the brain, has emerged as a key sensor of blood-borne signals. In both the ARC and white adipose tissue (WAT), consumption of a high-fat diet (HFD) rapid...

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Bibliographic Details
Main Authors: Yi, Chun-Xia, Tschöp, Matthias H., Woods, Stephen C., Hofmann, Susanna M.
Format: Online
Language:English
Published: The Company of Biologists Limited 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424466/