Apoptosis of Human Islet Cells by Cytokines
FasL, perforin, TNFα, IL-1 and NO have been considered as effector molecule(s) leading to β-cell death in autoimmune diabetes. However, the real culprit(s) of β-cell destruction have long been elusive despite intense investigation. Previously we have suggested IFNγ/TNFα synergism as the final effect...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Korean Association of Immunologists
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422709/ |