HIV p24 as Scaffold for Presenting Conformational HIV Env Antigens

Heterologous protein scaffolds engrafted with structurally defined HIV Env epitopes recognized by broadly neutralizing monoclonal antibodies (MAbs) represent a promising strategy to elicit broad neutralizing antibodies. In such regards, a protein scaffold based on the HIV p24 CA protein is a highly...

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Bibliographic Details
Main Authors: Tagliamonte, Maria, Marasco, Daniela, Ruggiero, Alessia, De Stradis, Angelo, Tornesello, Maria Lina, Totrov, Maxim, Buonaguro, Franco Maria, Buonaguro, Luigi
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422313/