A Novel Highly Potent Therapeutic Antibody Neutralizes Multiple Human Chemokines and Mimics Viral Immune Modulation

A Novel Highly Potent Therapeutic Antibody Neutralizes Multiple Human Chemokines and Mimics Viral Immune Modulation

Chemokines play a key role in leukocyte recruitment during inflammation and are implicated in the pathogenesis of a number of autoimmune diseases. As such, inhibiting chemokine signaling has been of keen interest for the development of therapeutic agents. This endeavor, however, has been hampered du...

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Bibliographic Details
Main Authors: Scalley-Kim, Michelle L., Hess, Bruce W., Kelly, Ryan L., Krostag, Anne-Rachel F., Lustig, Kurt H., Marken, John S., Ovendale, Pamela J., Posey, Aaron R., Smolak, Pamela J., Taylor, Janelle D. L., Wood, C. L., Bienvenue, David L., Probst, Peter, Salmon, Ruth A., Allison, Daniel S., Foy, Teresa M., Raport, Carol J.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422223/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422223/

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