The glucose-deprivation network counteracts lapatinib-induced toxicity in resistant ErbB2-positive breast cancer cells
This study implicates the glucose deprivation response in breast cancer cell resistance to lapatinib and high relapse rates in Her2-positive patients. Identification of these compensatory networks suggests novel strategies to target cancer signaling and metabolism.
Bibliographic Details
| Main Authors: |
Komurov, Kakajan,
Tseng, Jen-Te,
Muller, Melissa,
Seviour, Elena G,
Moss, Tyler J,
Yang, Lifeng,
Nagrath, Deepak,
Ram, Prahlad T |
|---|
| Format: | Online
|
|---|
| Language: | English |
|---|
| Published: |
Nature Publishing Group
2012
|
|---|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3421441/
|
|---|