Priapism in Antipsychotic Drug Use: A Rare but Important Side Effect
Priapism is a rare but important side effect of antipsychotic drugs which may evolve into a urological emergency. Most antipsychotic drugs are alpha-1 adrenergic antagonists, which is thought to be the principal mechanism involved in antipsychotic-induced priapism. Other aetiologies exist, however....
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| Format: | Online |
| Language: | English |
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Hindawi Publishing Corporation
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420524/ |
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pubmed-3420524 |
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pubmed-34205242012-08-29 Priapism in Antipsychotic Drug Use: A Rare but Important Side Effect Sinkeviciute, Igne Kroken, Rune A. Johnsen, Erik Case Report Priapism is a rare but important side effect of antipsychotic drugs which may evolve into a urological emergency. Most antipsychotic drugs are alpha-1 adrenergic antagonists, which is thought to be the principal mechanism involved in antipsychotic-induced priapism. Other aetiologies exist, however. A case is presented with multiple episodes of priapism during the use of several different antipsychotic drugs. The case is representative of many patients treated with antipsychotic drugs, as there were hyperprolactinemia, and illicit drug use, which are known causes of priapism. Moreover, the patient used combinations of antipsychotic drugs. The case thus illustrates the etiological complexity which could delay a diagnosis of antipsychotic-induced priapism, and the problem of establishing a link between priapism and one particular ingredient of a drug combination. The case presents how a treatment regimen was finally established balancing antipsychotic efficacy to acceptable side effects and offers guidance to physicians regarding how antipsychotic-induced priapism may be resolved. Hindawi Publishing Corporation 2012 2012-06-05 /pmc/articles/PMC3420524/ /pubmed/22934218 http://dx.doi.org/10.1155/2012/496364 Text en Copyright © 2012 Igne Sinkeviciute et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Sinkeviciute, Igne Kroken, Rune A. Johnsen, Erik |
| spellingShingle |
Sinkeviciute, Igne Kroken, Rune A. Johnsen, Erik Priapism in Antipsychotic Drug Use: A Rare but Important Side Effect |
| author_facet |
Sinkeviciute, Igne Kroken, Rune A. Johnsen, Erik |
| author_sort |
Sinkeviciute, Igne |
| title |
Priapism in Antipsychotic Drug Use: A Rare but Important Side Effect |
| title_short |
Priapism in Antipsychotic Drug Use: A Rare but Important Side Effect |
| title_full |
Priapism in Antipsychotic Drug Use: A Rare but Important Side Effect |
| title_fullStr |
Priapism in Antipsychotic Drug Use: A Rare but Important Side Effect |
| title_full_unstemmed |
Priapism in Antipsychotic Drug Use: A Rare but Important Side Effect |
| title_sort |
priapism in antipsychotic drug use: a rare but important side effect |
| description |
Priapism is a rare but important side effect of antipsychotic drugs which may evolve into a urological emergency. Most antipsychotic drugs are alpha-1 adrenergic antagonists, which is thought to be the principal mechanism involved in antipsychotic-induced priapism. Other aetiologies exist, however. A case is presented with multiple episodes of priapism during the use of several different antipsychotic drugs. The case is representative of many patients treated with antipsychotic drugs, as there were hyperprolactinemia, and illicit drug use, which are known causes of priapism. Moreover, the patient used combinations of antipsychotic drugs. The case thus illustrates the etiological complexity which could delay a diagnosis of antipsychotic-induced priapism, and the problem of establishing a link between priapism and one particular ingredient of a drug combination. The case presents how a treatment regimen was finally established balancing antipsychotic efficacy to acceptable side effects and offers guidance to physicians regarding how antipsychotic-induced priapism may be resolved. |
| publisher |
Hindawi Publishing Corporation |
| publishDate |
2012 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420524/ |
| _version_ |
1611550150097895424 |