Cellular Cofactors of Lentiviral Integrase: From Target Validation to Drug Discovery
To accomplish their life cycle, lentiviruses make use of host proteins, the so-called cellular cofactors. Interactions between host cell and viral proteins during early stages of lentiviral infection provide attractive new antiviral targets. The insertion of lentiviral cDNA in a host cell chromosome...
Main Authors: | , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420096/ |