Potential Canonical Wnt Pathway Activation in High-Grade Astrocytomas

Potential Canonical Wnt Pathway Activation in High-Grade Astrocytomas

Aberrant wnt pathway activation through cytoplasmic stabilization of β-catenin is crucial for the development of various human malignancies. In gliomagenesis, the role of canonical (i.e., β-catenin-dependent) signalling is largely unknown. Here, we studied canonical wnt pathway activation in 15 shor...

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Main Authors: Schüle, Rebecca, Dictus, Christine, Campos, Benito, Wan, Feng, Felsberg, Jörg, Ahmadi, Rezvan, Centner, Franz-Simon, Grabe, Niels, Reifenberger, Guido, Bermejo, Justo L., Unterberg, Andreas, Herold-Mende, Christel
Format: Online
Language:English
Published: The Scientific World Journal 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419426/

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