Haemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish

This in vivo time-lapse imaging study in zebrafish reveals how changes to brain blood flow drive vessel pruning via endothelial cell migration, and how pruning leads to the simplification of the brain vasculature during development.

Bibliographic Details
Main Authors: Chen, Qi, Jiang, Luan, Li, Chun, Hu, Dan, Bu, Ji-wen, Cai, David, Du, Jiu-lin
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419171/