Characterization of an apical ceramide-enriched compartment regulating ciliogenesis
The sphingolipid ceramide is essential for the formation, elongation, or maintenance of primary cilia. A novel, apical ceramide-enriched compartment induces formation of a ciliogenic protein complex with Rab11a, which sustains formation and maintenance of primary cilia by preventing deacetylation of...
| Main Authors: | , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418310/ |