Pac-man motility of kinetochores unleashed by laser microsurgery

Experiments reveal pac-man motility in kinetochores of X-Y chromosomes, even though their normal behavior is dominated by traction fiber mechanics. A laser microbeam is used to release kinetochores in anaphase from tension. There is a poleward motion of released kinetochores twice as fast as normal...

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Bibliographic Details
Main Authors: LaFountain, James R., Cohan, Christopher S., Oldenbourg, Rudolf
Format: Online
Language:English
Published: The American Society for Cell Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418308/