Inference of Selection Based on Temporal Genetic Differentiation in the Study of Highly Polymorphic Multigene Families

The co-evolutionary arms race between host immune genes and parasite virulence genes is known as Red Queen dynamics. Temporal fluctuations in allele frequencies, or the ‘turnover’ of alleles at immune genes, are concordant with predictions of the Red Queen hypothesis. Such observations are often tak...

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Bibliographic Details
Main Authors: McMullan, Mark, van Oosterhout, Cock
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416836/