Hallmarks of human “immunosenescence”: adaptation or dysregulation?
Is immunosenescence an intrinsic ageing process leading to dysregulation of immunity or an adaptive response of the individual to pathogen exposure? Age-associated differences in bone marrow immune cell output and thymic involution suggest the former. Accepted hallmarks of immunosenescence (decrease...
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Format: | Online |
Language: | English |
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BioMed Central
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416738/ |